Pulmonary Surfactant-Associated Protein C (SFTPC) Antibody

Catalogue No: abx001517
Price: £120.00
(Size: 20 µl)
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Pulmonary Surfactant-Associated Protein C (SFTPC) Antibody

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SFTPC Antibody is a Rabbit Polyclonal antibody against SFTPC. This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Target SFTPC
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SFTPC.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P11686 (UniProt, ExPASy)
UniProt Secondary AC A6XNE4, B2RE00, E9PGX3, P11687, Q12793, Q7Z5D0
UniProt Entry Name PSPC_HUMAN
Gene Symbol SFTPC
GeneID 6440
KEGG hsa:6440
String 9606.ENSP00000316152
Molecular Weight Calculated MW: 20 kDa, 21 kDa
Observed MW: 21 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.17 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Pulmonary Surfactant-Associated Protein C (SFTPC) Antibody

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