Serine/Threonine-Protein Kinase Sgk1 (SGK1) Antibody

SGK1 Antibody is a Rabbit Polyclonal antibody against SGK1. This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Target	Serine/Threonine-Protein Kinase Sgk1 (SGK1)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 172-431 of human SGK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00141 (UniProt, ExPASy)
UniProt Entry Name	SGK1_HUMAN
Gene Symbol	SGK1
GeneID	6446
NCBI Accession	NP_005618.2
KEGG	hsa:6446
String	9606.ENSP00000356832
Molecular Weight	Calculated MW: 49 kDa Observed MW: 45-60 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/Threonine-Protein Kinase Sgk1 (SGK1)

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