Serine/Threonine-Protein Kinase Sgk1 (SGK1) Antibody

SGK1 Antibody is a Rabbit Polyclonal antibody against SGK1. Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to AktSGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoidsSGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathwaysInduction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulationSGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretionSGK is negatively regulated by ubiquitination and proteasome degradationThe MAP kinase family member BMK1 interacts with and activates SGK by phosphorylation at serine 78.

Target	Serine/Threonine-Protein Kinase Sgk1 (SGK1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant protein of human SGK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00141 (UniProt, ExPASy)
UniProt Entry Name	SGK1_HUMAN
Gene Symbol	SGK1
GeneID	6446
KEGG	hsa:6446
String	9606.ENSP00000356832
Buffer	PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/Threonine-Protein Kinase Sgk1 (SGK1)

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