Serine Hydroxymethyltransferase, Mitochondrial (SHMT2) Antibody
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Catalogue No: abx001127
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US$348.00
(Size: 60 µl)
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Datasheet SDS
SHMT2 Antibody is a Rabbit Polyclonal antibody against SHMT2. This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Research Articles on Serine Hydroxymethyltransferase, Mitochondrial (SHMT2)
| Target | Serine Hydroxymethyltransferase, Mitochondrial (SHMT2) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human SHMT2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P34897 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z9F1, E7EQ19, E7EU43, O00740, Q8N1A5 |
| UniProt Entry Name | GLYM_HUMAN |
| Gene Symbol | SHMT2 |
| GeneID | 6472 |
| NCBI Accession | NP_005403.2 |
| KEGG | hsa:6472 |
| String | 9606.ENSP00000333667 |
| Molecular Weight | Calculated MW: 53 kDa/54 kDa/55 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
