E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Antibody

Catalogue No: abx001938
Price: £120.00
(Size: 20 µl)
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SIAH1 Antibody is a Rabbit Polyclonal antibody against SIAH1. This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Target SIAH1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SIAH1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8IUQ4 (UniProt, ExPASy)
UniProt Secondary AC A0FKF3, O43269, Q49A58, Q92880
UniProt Entry Name SIAH1_HUMAN
Gene Symbol SIAH1
GeneID 6477
KEGG hsa:6477
String 9606.ENSP00000349156
Molecular Weight Calculated MW: 21 kDa, 31 kDa, 34 kDa
Observed MW: 31 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SIAH1

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