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Target | Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) |
Clonality | Monoclonal |
Clone | C658 |
Reactivity | Human, Monkey |
Tested Applications | FCM |
Host | Mouse |
Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | PE |
Excitation/Emission | 565/575 |
Laser Line | 550 |
Immunogen | Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1. |
Isotype | IgG1 |
Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
UniProt Primary AC | O15389 (UniProt, ExPASy) |
Gene Symbol | SIGLEC5 |
GeneID | 8778 |
KEGG | hsa:8778 |
String | 9606.ENSP00000470259 |
Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
Specificity | The mouse monoclonal antibody recognizes CD170 (Siglec-5, sialic acid binding Ig-like lectin 5), a transmembrane glycoprotein expressed strongly by neutrophils, macrophages activated during infections, monocytes, and dendritic cells. As in case with other anti-CD170 antibodies, this antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170. |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |