Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) Antibody

Catalogue No: abx003149
Price: £120.00
(Size: 20 µl)
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SIGLEC5 Antibody is a Rabbit Polyclonal antibody against SIGLEC5. This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Target SIGLEC5
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SIGLEC5.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15389 (UniProt, ExPASy)
UniProt Entry Name SIGL5_HUMAN
Gene Symbol SIGLEC5
GeneID 8778
KEGG hsa:8778
String 9606.ENSP00000470259
Molecular Weight Calculated MW: 60 kDa
Observed MW: 75 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SIGLEC5

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