Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) Antibody
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Catalogue No: abx003149
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US$217.50
(Size: 20 µl)
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Datasheet SDS
SIGLEC5 Antibody is a Rabbit Polyclonal antibody against SIGLEC5. This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Research Articles on Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5)
| Target | Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) |
| Research Area | Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to SIGLEC5. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15389 (UniProt, ExPASy) |
| UniProt Entry Name | SIGL5_HUMAN |
| Gene Symbol | SIGLEC5 |
| GeneID | 8778 |
| NCBI Accession | NP_003821.1 |
| KEGG | hsa:8778 |
| String | 9606.ENSP00000470259 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |