Signal Regulatory Protein Beta 1 (SIRPB1) Antibody

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Target	Signal Regulatory Protein Beta 1 (SIRPB1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00241 (UniProt, ExPASy)
UniProt Secondary AC	A6NLM2, B2R8V0, Q5TFQ9, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0
UniProt Entry Name	SIRB1_HUMAN
Gene Symbol	SIRPB1
String	9606.ENSP00000371018
Molecular Weight	Calculated MW: 43.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Signal Regulatory Protein Beta 1 (SIRPB1)

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