Sirtuin 1 (SIRT1) Antibody

Catalogue No: abx000615
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
SIRT1 Antibody is a Rabbit Polyclonal antibody against SIRT1. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Target SIRT1
Clonality Polyclonal
Reactivity Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide. C term -peptide of human SIRT1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96EB6 (UniProt, ExPASy)
UniProt Secondary AC Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0
UniProt Entry Name SIR1_HUMAN
Gene Symbol SIRT1
GeneID 23411
KEGG hsa:23411
String 9606.ENSP00000212015
Molecular Weight Calculated MW: 61 kDa, 81 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SIRT1

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