Sirtuin 2 (SIRT2) Antibody

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Catalogue No: abx000658
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
SIRT2 Antibody is a Rabbit Polyclonal antibody against SIRT2. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.

Target Sirtuin 2 (SIRT2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 300-350 of human SIRT2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8IXJ6 (UniProt, ExPASy)
UniProt Entry Name SIR2_HUMAN
Gene Symbol SIRT2
GeneID 22933
NCBI Accession NP_036369.2
KEGG hsa:22933
String 9606.ENSP00000249396
Molecular Weight Calculated MW: 43 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Sirtuin 2 (SIRT2)


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