Sirtuin 7 (SIRT7) Antibody

SIRT7 Antibody is a Rabbit Polyclonal antibody against SIRT7. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008].

Target	Sirtuin 7 (SIRT7)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 201-400 of human SIRT7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NRC8 (UniProt, ExPASy)
UniProt Secondary AC	A8K2K0, B3KSU8, Q3MIK4, Q9NSZ6, Q9NUS6
UniProt Entry Name	SIR7_HUMAN
Gene Symbol	SIRT7
GeneID	51547
NCBI Accession	NP_057622.1
String	9606.ENSP00000329466
Molecular Weight	Calculated MW: 45 kDa Observed MW: 45 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sirtuin 7 (SIRT7)

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