Src Kinase Associated Phosphoprotein 1 (SKAP1) Antibody

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

Target	Src Kinase Associated Phosphoprotein 1 (SKAP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human SKAP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q86WV1 (UniProt, ExPASy)
UniProt Secondary AC	D3DTV1, O15268
UniProt Entry Name	SKAP1_HUMAN
Gene Symbol	SKAP1
KEGG	hsa:8631
String	9606.ENSP00000338171
Molecular Weight	Calculated MW: 41.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Src Kinase Associated Phosphoprotein 1 (SKAP1)

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