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S-Phase Kinase Associated Protein 1 (SKP1) Antibody
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Catalogue No: abx002003
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US$217.50
(Size: 20 µl)
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Datasheet SDS
SKP1 Antibody is a Rabbit Polyclonal antibody against SKP1. This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Research Articles on S-Phase Kinase Associated Protein 1 (SKP1)
| Target | S-Phase Kinase Associated Protein 1 (SKP1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to SKP1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P63208 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQ97, D3DQ98, P34991, Q8TAY2 |
| UniProt Entry Name | SKP1_HUMAN |
| Gene Symbol | SKP1 |
| GeneID | 6500 |
| NCBI Accession | NP_733779.1 |
| KEGG | hsa:6500 |
| String | 9606.ENSP00000231487 |
| Molecular Weight | Calculated MW: 19 kDa Observed MW: 19 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |