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Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody

Catalogue No: abx001661
Price: £120.00
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Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody

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SLAMF1 Antibody is a Rabbit Polyclonal antibody against SLAMF1. Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP).

Target Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SLAMF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13291 (UniProt, ExPASy)
UniProt Secondary AC Q5W172, Q9HBE8, W0HKK7
UniProt Entry Name SLAF1_HUMAN
Gene Symbol SLAMF1
GeneID 6504
KEGG hsa:6504
String 9606.ENSP00000306190
Molecular Weight Calculated MW: 33 kDa, 37 kDa, 40 kDa
Observed MW: 37 kDa, 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody

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