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Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody
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Catalogue No: abx001661
Price:
US$217.50
(Size: 20 µl)
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SLAMF1 Antibody is a Rabbit Polyclonal antibody against SLAMF1. Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP).
Research Articles on Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1)
| Target | Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to SLAMF1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13291 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5W172, Q9HBE8, W0HKK7 |
| UniProt Entry Name | SLAF1_HUMAN |
| Gene Symbol | SLAMF1 |
| GeneID | 6504 |
| NCBI Accession | NP_003028.1 |
| KEGG | hsa:6504 |
| String | 9606.ENSP00000306190 |
| Molecular Weight | Calculated MW: 37 kDa Observed MW: 37/65 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |