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Signaling Lymphocytic Activation Molecule Family Member 1 Phospho-Tyr281 (SLAMF1 pY281) Antibody
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Catalogue No: abx032024
Price:
US$326.25
(Size: 80 µl)
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SLAMF1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (pYPN11) dependent signal transduction operates.
Research Articles on Signaling Lymphocytic Activation Molecule Family Member 1 Phospho-Tyr281 (SLAMF1 pY281)
| Target | Signaling Lymphocytic Activation Molecule Family Member 1 Phospho-Tyr281 (SLAMF1 pY281) |
| Clonality | Polyclonal |
| Target Modification | Tyr281 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y281 of human SLAMF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13291 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5W172, Q9HBE8, W0HKK7 |
| UniProt Entry Name | SLAF1_HUMAN |
| KEGG | hsa:6504 |
| String | 9606.ENSP00000306190 |
| Molecular Weight | Calculated MW: 37.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |