Natural Resistance-Associated Macrophage Protein 1 (SLC11A1) Antibody
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Catalogue No: abx033976
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US$326.25
(Size: 80 µl)
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Datasheet SDS
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Research Articles on Natural Resistance-Associated Macrophage Protein 1 (SLC11A1)
| Target | Natural Resistance-Associated Macrophage Protein 1 (SLC11A1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 250-276 amino acids from the Central region of human SLC11A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49279 (UniProt, ExPASy) |
| UniProt Secondary AC | C0H5Y3 |
| UniProt Entry Name | NRAM1_HUMAN |
| Gene Symbol | SLC11A1 |
| GeneID | 6556 |
| HGNC | 10907 |
| KEGG | hsa:6556 |
| String | 9606.ENSP00000233202 |
| Molecular Weight | Calculated MW: 59.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |