Natural Resistance-Associated Macrophage Protein 1 (SLC11A1) Antibody

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Catalogue No: abx033976
Price: US$290.00
(Size: 80 µl)

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Datasheet SDS
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

Target Natural Resistance-Associated Macrophage Protein 1 (SLC11A1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 250-276 amino acids from the Central region of human SLC11A1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49279 (UniProt, ExPASy)
UniProt Secondary AC C0H5Y3
UniProt Entry Name NRAM1_HUMAN
Gene Symbol SLC11A1
GeneID 6556
HGNC 10907
KEGG hsa:6556
String 9606.ENSP00000233202
Molecular Weight Calculated MW: 59.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Natural Resistance-Associated Macrophage Protein 1 (SLC11A1)


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