Monocarboxylate Transporter 4 / MCT4 (SLC16A3) Antibody
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Catalogue No: abx026782
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
Research Articles on Monocarboxylate Transporter 4 / MCT4 (SLC16A3)
| Target | Monocarboxylate Transporter 4 / MCT4 (SLC16A3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 433-462 amino acids from the C-terminal region of human SLC16A3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15427 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KXG8, Q2M1P8 |
| UniProt Entry Name | MOT4_HUMAN |
| Gene Symbol | SLC16A3 |
| KEGG | hsa:9123 |
| String | 9606.ENSP00000463978 |
| Molecular Weight | Calculated MW: 49.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat SLC16A3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |