Mothers Against Decapentaplegic Homolog 6 (SMAD6) Antibody

SMAD6 Antibody is a Rabbit Polyclonal antibody against SMAD6. The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Mothers Against Decapentaplegic Homolog 6 (SMAD6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43541 (UniProt, ExPASy)
UniProt Secondary AC	A9J6M5, O43654, Q15799, Q7Z7L4, Q96E31, Q9UKZ3
UniProt Entry Name	SMAD6_HUMAN
Gene Symbol	SMAD6
GeneID	4091
NCBI Accession	NP_005576.3
KEGG	hsa:4091
String	9606.ENSP00000288840
Molecular Weight	Calculated MW: 53 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mothers Against Decapentaplegic Homolog 6 (SMAD6)

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