U5 Small Nuclear Ribonucleoprotein 200 kDa Helicase (SNRNP200) Antibody
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Catalogue No: abx004666
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US$348.00
(Size: 60 µl)
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Datasheet SDS
SNRNP200 Antibody is a Rabbit Monoclonal antibody against SNRNP200. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Research Articles on U5 Small Nuclear Ribonucleoprotein 200 kDa Helicase (SNRNP200)
| Target | U5 Small Nuclear Ribonucleoprotein 200 kDa Helicase (SNRNP200) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human SNRNP200 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75643 (UniProt, ExPASy) |
| UniProt Secondary AC | O94884, Q6NZY0, Q6PX59, Q8NBE6, Q96IF2, Q9H7S0 |
| UniProt Entry Name | U520_HUMAN |
| Gene Symbol | SNRNP200 |
| GeneID | 23020 |
| NCBI Accession | NP_054733.2 |
| KEGG | hsa:23020 |
| String | 9606.ENSP00000317123 |
| Molecular Weight | Calculated MW: 71 kDa/244 kDa Observed MW: 244 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
