Snurportin 1 (SNUPN) Antibody

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2, 2, 7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Target	Snurportin 1 (SNUPN)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 200-228 amino acids from the Central region of human SNUPN.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95149 (UniProt, ExPASy)
UniProt Secondary AC	A6NE34, A8K0B0, D3DW76
UniProt Entry Name	SPN1_HUMAN
Gene Symbol	SNUPN
KEGG	hsa:10073
String	9606.ENSP00000454852
Molecular Weight	Calculated MW: 41.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Snurportin 1 (SNUPN)

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