Suppressors of Cytokine Signaling 3 (SOCS3) Antibody

Catalogue No: abx000853
Price: £120.00
(Size: 20 µl)
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SOCS3 Antibody is a Rabbit Polyclonal antibody against SOCS3. The suppressor of cytokine signaling (SOCS) family proteins are negative feedback system that inhibits cytokine signal transduction. One of the SOCS family, SOCS3, also named as CIS3 and SSI3, is involved in inhibition of JAK/STAT pathway which regulates IL-6 signaling in vivo. SOCS3 can be rapidly trigger by a number of factors including interleukins, IFN-gamma and TNF-alpha. Pathology such as inflammatory response, wound repair and obesity and so on have been linked to SOCS3. This antibody was raised against the full-length SOCS3 of human origin.

Target SOCS3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SOCS3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14543 (UniProt, ExPASy)
UniProt Secondary AC O14509
UniProt Entry Name SOCS3_HUMAN
Gene Symbol SOCS3
GeneID 9021
KEGG hsa:9021
String 9606.ENSP00000330341
Molecular Weight Calculated MW: 24 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SOCS3

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