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Transcription Factor SOX-2 (SOX2) Antibody
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Catalogue No: abx011547
Price:
US$427.75
(Size: 100 µl)
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SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Research Articles on Transcription Factor SOX-2 (SOX2)
| Target | Transcription Factor SOX-2 (SOX2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of SOX2 (aa1-170) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48431 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14537 |
| UniProt Entry Name | SOX2_HUMAN |
| Gene Symbol | SOX2 |
| GeneID | 6657 |
| OMIM | 184429 |
| HGNC | 11195 |
| KEGG | hsa:6657 |
| Ensembl | ENSG00000181449 |
| String | 9606.ENSP00000323588 |
| Molecular Weight | 34.3 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |