Sex Determining Region Y Box Protein 2 (SOX2) Antibody

Catalogue No: abx000763
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Sex Determining Region Y Box Protein 2 (SOX2) Antibody Sex Determining Region Y Box Protein 2 (SOX2) Antibody Sex Determining Region Y Box Protein 2 (SOX2) Antibody

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SOX2 Antibody is a Rabbit Polyclonal antibody against SOX2. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Target SOX2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SOX2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48431 (UniProt, ExPASy)
UniProt Secondary AC Q14537
UniProt Entry Name SOX2_HUMAN
Gene Symbol SOX2
GeneID 6657
KEGG hsa:665
String 9606.ENSP00000323588
Molecular Weight Calculated MW: 34 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Sex Determining Region Y Box Protein 2 (SOX2) Antibody

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