SP600125

SP600125 is a small molecule. Selective inhibitor of c-Jun N-terminal kinase (JNK). Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes (IC50 > 10 µM). Active in vivo. Shown to have reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis.

Target	SP600125
Origin	Synthetic
Form	Solid
Purity	>98%
Storage	Store at -20 °C.
Molecular Weight	220.2 g/mol
Molecular Formula	C14H8N2O
CAS Number	129-56-6
SMILES	C1=CC=C4C3=C1C(=O)C2=CC=CC=C2C3=N[NH]4
Availability	Shipped within 5-12 working days.
Note	This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Research Articles on SP600125

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