Serine/Threonine-Protein Kinase 39 (SPAK) Antibody
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Catalogue No: abx028087
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US$326.25
(Size: 80 µl)
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Datasheet SDS
STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
Research Articles on Serine/Threonine-Protein Kinase 39 (SPAK)
| Target | Serine/Threonine-Protein Kinase 39 (SPAK) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UEW8 (UniProt, ExPASy) |
| UniProt Secondary AC | O14774, Q53S90, Q53SL7, Q53SS1, Q9UER4, X5D9C8 |
| UniProt Entry Name | STK39_HUMAN |
| NCBI Accession | NP_037365.2 |
| String | 9606.ENSP00000348278 |
| Molecular Weight | Calculated MW: 59.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat STK39. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |