SPARC (SPARC) Antibody

SPARC Antibody is a Rabbit Polyclonal antibody against SPARC. This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion.

Target	SPARC (SPARC)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	IHC
Host	Rabbit
Recommended dilutions	IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human SPARC.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P09486 (UniProt, ExPASy)
UniProt Secondary AC	D3DQH9, Q6IBK4
UniProt Entry Name	SPRC_HUMAN
Gene Symbol	SPARC
GeneID	6678
NCBI Accession	NP_003109.1
KEGG	hsa:6678
String	9606.ENSP00000231061
Molecular Weight	Calculated MW: 35 kDa Observed MW: 35 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on SPARC (SPARC)

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