Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1) Antibody

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human SPI1 (AA: 124-271) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17947 (UniProt, ExPASy)
UniProt Entry Name	SPI1_HUMAN
Gene Symbol	SPI1
GeneID	6688
OMIM	165170
HGNC	11241
KEGG	hsa:6688
Ensembl	ENSG00000066336
String	9606.ENSP00000227163
Molecular Weight	42 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1)

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