Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1) Antibody

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Target	Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human SPI1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17947 (UniProt, ExPASy)
UniProt Entry Name	SPI1_HUMAN
Gene Symbol	SPI1
KEGG	hsa:6688
String	9606.ENSP00000227163
Molecular Weight	Calculated MW: 31.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Pig SPI1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Spleen Focus Forming Virus Proviral Integration Oncogene (SPI1)

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