Serine Peptidase Inhibitor Kunitz Type 2 (SPINT2) Antibody

SPINT2 Antibody is a Rabbit Polyclonal antibody against SPINT2. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Serine Peptidase Inhibitor Kunitz Type 2 (SPINT2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 28-197 of human SPINT2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43291 (UniProt, ExPASy)
UniProt Secondary AC	A8K667, B4DLU1, O00271, O14895, Q5TZQ3, Q969E0
UniProt Entry Name	SPIT2_HUMAN
Gene Symbol	SPINT2
GeneID	10653
NCBI Accession	NP_066925.1
KEGG	hsa:10653
String	9606.ENSP00000301244
Molecular Weight	Calculated MW: 28 kDa Observed MW: 34 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine Peptidase Inhibitor Kunitz Type 2 (SPINT2)

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