Osteopontin (SPP1) Antibody
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Catalogue No: abx011873
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on Osteopontin (SPP1)
| Target | Osteopontin (SPP1) |
| Research Area | Tumor Immunity, Bone Metabolism, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10451 (UniProt, ExPASy) |
| UniProt Entry Name | OSTP_HUMAN |
| Gene Symbol | SPP1 |
| GeneID | 6696 |
| OMIM | 166490 |
| HGNC | 11255 |
| KEGG | hsa:6696 |
| Ensembl | ENSG00000118785 |
| String | 9606.ENSP00000378517 |
| Molecular Weight | 35.4 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |