Osteopontin (SPP1) Antibody

Catalogue No: abx001202
Price: £120.00
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Osteopontin (SPP1) Antibody

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SPP1 Antibody is a Rabbit Polyclonal antibody against SPP1. Osteopontin (OPN), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPN isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.

Target SPP1
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SPP1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10451 (UniProt, ExPASy)
UniProt Entry Name OSTP_HUMAN
Gene Symbol SPP1
GeneID 6696
KEGG hsa:6696
String 9606.ENSP00000378517
Molecular Weight Calculated MW: 32 kDa, 33 kDa, 35 kDa
Observed MW: 38 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Osteopontin (SPP1) Antibody

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