Osteopontin (SPP1) Antibody
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Catalogue No: abx001202
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US$217.50
(Size: 20 µl)
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Datasheet SDS
SPP1 Antibody is a Rabbit Polyclonal antibody against SPP1. Osteopontin (SPP1), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. SPP1 is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While SPP1 is a major product of osteoblasts, it is also synthesized by brain and kidney cells. SPP1 isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. SPP1 functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.
Research Articles on Osteopontin (SPP1)
| Target | Osteopontin (SPP1) |
| Research Area | Tumor Immunity, Bone Metabolism, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to SPP1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10451 (UniProt, ExPASy) |
| UniProt Entry Name | OSTP_HUMAN |
| Gene Symbol | SPP1 |
| GeneID | 6696 |
| NCBI Accession | NP_001035147.1 |
| KEGG | hsa:6696 |
| String | 9606.ENSP00000378517 |
| Molecular Weight | Calculated MW: 35 kDa Observed MW: 45-70 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |