Sequestosome 1 Phospho-Ser403 (SQSTM1 pS403) Antibody
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Catalogue No: abx032211
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Research Articles on Sequestosome 1 Phospho-Ser403 (SQSTM1 pS403)
| Target | Sequestosome 1 Phospho-Ser403 (SQSTM1 pS403) |
| Clonality | Polyclonal |
| Target Modification | Ser403 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13501 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NFN7, B2R661, B3KUW5, Q13446, Q9BUV7, Q9BVS6, Q9UEU1 |
| UniProt Entry Name | SQSTM_HUMAN |
| Gene Symbol | SQSTM1 |
| GeneID | 8878 |
| OMIM | 167250 |
| HGNC | 11280 |
| KEGG | hsa:8878 |
| Ensembl | ENSG00000161011 |
| String | 9606.ENSP00000374455 |
| Molecular Weight | Calculated MW: 47.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat SQSTM1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |