SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) Antibody

SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian).This gene is highly similar to the v-src gene of Rous sarcoma virus.This proto-oncogene may play a role in the regulation of embryonic development and cell growth.The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase.Mutations in this gene could be involved in the malignant progression of colon cancer.Two transcript variants encoding the same protein have been found for this gene.

Target	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of SRC (aa10-193) expressed in E. coli.
Isotype	IgG2a
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12931 (UniProt, ExPASy)
UniProt Secondary AC	E1P5V4, Q76P87, Q86VB9, Q9H5A8
Gene Symbol	SRC
GeneID	6714
OMIM	190090
HGNC	11283
Ensembl	ENSG00000197122
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC)

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