Sushi Repeat Containing Protein, X-Linked (SRPX) Antibody

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Catalogue No: abx001129
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
SRPX Antibody is a Rabbit Polyclonal antibody against SRPX. X-linked retinitis pigmentosa (XLRP) is a retinal degeneration disorder. The most common form of XLRP has been localized to the gene locus RP3 by linkage and deletion analysis. RP3 maps to chromosome Xp21.1 between CYBB and OTC. The sushi-repeat-containing protein, x chromosome (SRPX) gene, also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.

Target Sushi Repeat Containing Protein, X-Linked (SRPX)
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human SRPX.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P78539 (UniProt, ExPASy)
UniProt Entry Name SRPX_HUMAN
Gene Symbol SRPX
GeneID 8406
NCBI Accession NP_006298.1
KEGG hsa:8406
String 9606.ENSP00000367794
Molecular Weight Calculated MW: 52 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Sushi Repeat Containing Protein, X-Linked (SRPX)


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