Lupus La Protein (SSB) Antibody

SSB Antibody is a Rabbit Polyclonal antibody against SSB. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus.

Target	Lupus La Protein (SSB)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 166-408 of human SSB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05455 (UniProt, ExPASy)
UniProt Secondary AC	Q15367, Q53XJ4
UniProt Entry Name	LA_HUMAN
Gene Symbol	SSB
GeneID	6741
NCBI Accession	NP_003133.1
KEGG	hsa:6741
String	9606.ENSP00000386636
Molecular Weight	Calculated MW: 47 kDa Observed MW: 47 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lupus La Protein (SSB)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue