Structure Specific Recognition Protein 1 (SSRP1) Antibody

SSRP1 Antibody is a Rabbit Polyclonal antibody against SSRP1. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Target	Structure Specific Recognition Protein 1 (SSRP1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SSRP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q08945 (UniProt, ExPASy)
UniProt Secondary AC	Q5BJG8
UniProt Entry Name	SSRP1_HUMAN
Gene Symbol	SSRP1
GeneID	6749
NCBI Accession	NP_003137.1
KEGG	hsa:6749
String	9606.ENSP00000278412
Molecular Weight	Calculated MW: 81 kDa Observed MW: 90 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Structure Specific Recognition Protein 1 (SSRP1)

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