Suppression Of Tumorigenicity 14 (ST14) Antibody

ST14 Antibody is a Rabbit Polyclonal antibody against ST14. The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Target	Suppression Of Tumorigenicity 14 (ST14)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y5Y6 (UniProt, ExPASy)
UniProt Secondary AC	Q9BS01, Q9H3S0, Q9HB36, Q9HCA3
UniProt Entry Name	ST14_HUMAN
Gene Symbol	ST14
GeneID	6768
NCBI Accession	NP_068813.1
String	9606.ENSP00000278742
Molecular Weight	Calculated MW: 95 kDa Observed MW: 95 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Suppression Of Tumorigenicity 14 (ST14)

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