Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) Antibody

Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2, 6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).

Target	Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human ST6GALNAC1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NSC7 (UniProt, ExPASy)
UniProt Secondary AC	Q6UW90, Q9NSC6
UniProt Entry Name	SIA7A_HUMAN
Gene Symbol	ST6GALNAC1
String	9606.ENSP00000156626
Molecular Weight	Calculated MW: 68.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha-N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 1 (ST6GALNAC1)

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