Signal Transducer And Activator of Transcription 1 (STAT1) Antibody
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Catalogue No: abx000529
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US$217.50
(Size: 20 µl)
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Datasheet SDS
STAT1 Antibody is a Rabbit Polyclonal antibody against STAT1. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Research Articles on Signal Transducer And Activator of Transcription 1 (STAT1)
| Target | Signal Transducer And Activator of Transcription 1 (STAT1) |
| Research Area | Signal Transduction, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/2000 - 1/6000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to STAT1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42224 (UniProt, ExPASy) |
| Gene Symbol | STAT1 |
| GeneID | 6772 |
| NCBI Accession | NP_009330.1 |
| Molecular Weight | Calculated MW: 87 kDa Observed MW: 84 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |