Signal Transducer And Activator of Transcription 1 Phospho-Ser727 (STAT1 pS727) Antibody

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Catalogue No: abx031918
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.

Target Signal Transducer And Activator of Transcription 1 Phospho-Ser727 (STAT1 pS727)
Clonality Polyclonal
Target Modification Ser727
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S727 of human STAT1.
Isotype IgG
Form Liquid
Purification Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P42224 (UniProt, ExPASy)
Molecular Weight Calculated MW: 87.3 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Pig STAT1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Signal Transducer And Activator of Transcription 1 Phospho-Ser727 (STAT1 pS727)


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