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Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690) Antibody

Catalogue No: abx000335
Price: £120.00
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Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690) Antibody

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STAT2 (pY690) Antibody is a Rabbit Polyclonal antibody against STAT2 (pY690). The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Target Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690)
Clonality Polyclonal
Target Modification Tyr690
Modification Phosphorylation
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y690 of human STAT2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52630 (UniProt, ExPASy)
UniProt Secondary AC B4DLC7, G3V2M6, Q16430, Q16431, Q9UDL4
UniProt Entry Name STAT2_HUMAN
Gene Symbol STAT2
GeneID 6773
KEGG hsa:6773
String 9606.ENSP00000315768
Molecular Weight Calculated MW: 97 kDa
Observed MW: 125 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690) Antibody

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