Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693) Antibody

Catalogue No: abx000189
Price: £230.00
(Size: 50 µl)
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STAT4 (pY693) Antibody is a Rabbit Polyclonal antibody against STAT4 (pY693). The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Target Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693)
Clonality Polyclonal
Target Modification Tyr693
Modification Phosphorylation
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14765 (UniProt, ExPASy)
UniProt Secondary AC Q96NZ6
UniProt Entry Name STAT4_HUMAN
Gene Symbol STAT4
GeneID 6775
KEGG hsa:6775
String 9606.ENSP00000376134
Molecular Weight Calculated MW: 85 kDa
Observed MW: 86 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Signal Transducer and Activator of Transcription 4 Phospho-Tyr693 (STAT4 pY693)

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