Staufen Double-Stranded RNA Binding Protein 1 (STAU1) Antibody

STAU1 Antibody is a Rabbit Polyclonal antibody against STAU1. Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.

Target	Staufen Double-Stranded RNA Binding Protein 1 (STAU1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 426-577 of human Staufen.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95793 (UniProt, ExPASy)
UniProt Entry Name	STAU1_HUMAN
Gene Symbol	STAU1
GeneID	6780
NCBI Accession	NP_059347.2
KEGG	hsa:6780
String	9606.ENSP00000360922
Molecular Weight	Calculated MW: 63 kDa Observed MW: 63 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Staufen Double-Stranded RNA Binding Protein 1 (STAU1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue