Stimulator of Interferon Genes Protein / TMEM173 (STING1) Antibody
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Catalogue No: abx240299
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US$406.00
(Size: 100 µg)
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Datasheet SDS
Stimulator of Interferon Genes Protein / TMEM173 (STING1) Antibody is a Mouse Monoclonal antibody for the detection of STING1. This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Research Articles on Stimulator of Interferon Genes Protein / TMEM173 (STING1)
| Target | Stimulator of Interferon Genes Protein / TMEM173 (STING1) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/5000, IHC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | transmembrane protein 173 |
| Isotype | IgG2b |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q86WV6 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3P6, B6EB35, D6RBX0, D6RE01, D6RID9 |
| UniProt Entry Name | STING_HUMAN |
| Gene Symbol | STING1 |
| GeneID | 340061 |
| OMIM | 612374 |
| HGNC | 27962 |
| KEGG | hsa:340061 |
| Ensembl | ENSG00000184584 |
| String | 9606.ENSP00000331288 |
| Molecular Weight | Observed MW: 39 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |