Stress-Induced-Phosphoprotein 1 (STIP1) Antibody

STIP1 Antibody is a Rabbit Polyclonal antibody against STIP1. STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM, Jul 2009]

Target	Stress-Induced-Phosphoprotein 1 (STIP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human STIP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P31948 (UniProt, ExPASy)
UniProt Secondary AC	B4DM70, F5H0T1, G3XAD8, Q3ZCU9, Q5TZU9
UniProt Entry Name	STIP1_HUMAN
Gene Symbol	STIP1
GeneID	10963
NCBI Accession	NP_006810.1
KEGG	hsa:10963
String	9606.ENSP00000351646
Molecular Weight	Calculated MW: 63 kDa Observed MW: 63 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Stress-Induced-Phosphoprotein 1 (STIP1)

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