SUFU Negative Regulator of Hedgehog Signaling (SUFU) Antibody
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Catalogue No: abx218817
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US$420.50
(Size: 100 µg)
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SUFU Negative Regulator of Hedgehog Signaling (SUFU) Antibody is a Rabbit Polyclonal antibody for the detection of SUFU. The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
Research Articles on SUFU Negative Regulator of Hedgehog Signaling (SUFU)
| Target | SUFU Negative Regulator of Hedgehog Signaling (SUFU) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | suppressor of fused homolog |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UMX1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0 |
| UniProt Entry Name | SUFU_HUMAN |
| Gene Symbol | SUFU |
| GeneID | 51684 |
| OMIM | 109400 |
| HGNC | 16466 |
| Ensembl | ENSG00000107882 |
| String | 9606.ENSP00000358918 |
| Molecular Weight | Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |