Small Ubiquitin-Related Modifier 4 (SUMO4) Antibody

SUMO4 Antibody is a Rabbit Polyclonal antibody against SUMO4. This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

Target	Small Ubiquitin-Related Modifier 4 (SUMO4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000, IHC-P: 1/100 - 1/300. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 40-95 of human SUMO4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q6EEV6 (UniProt, ExPASy)
UniProt Secondary AC	A1L3W5
UniProt Entry Name	SUMO4_HUMAN
Gene Symbol	SUMO4
GeneID	387082
KEGG	hsa:387082
String	9606.ENSP00000318635
Molecular Weight	Calculated MW: 11 kDa Observed MW: 18 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Small Ubiquitin-Related Modifier 4 (SUMO4)

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