Suppression Of Tumorigenicity 5 (ST5) Antibody

Suppression Of Tumorigenicity 5 (ST5) Antibody is a Rabbit Polyclonal antibody for the detection of ST5.

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Target	Suppression Of Tumorigenicity 5 (ST5)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	suppression of tumorigenicity 5
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P78524 (UniProt, ExPASy)
UniProt Entry Name	ST5_HUMAN
Gene Symbol	ST5
GeneID	6764
OMIM	140750
HGNC	11350
KEGG	hsa:6764
Ensembl	ENSG00000166444
String	9606.ENSP00000433528
Molecular Weight	Observed MW: 150 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Suppression Of Tumorigenicity 5 (ST5)

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