Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) Antibody

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Target	Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 187-214 amino acids from the Central region of human SUV4-20H2.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q86Y97 (UniProt, ExPASy)
UniProt Secondary AC	Q8WZ10, Q9BRZ6
UniProt Entry Name	KMT5C_HUMAN
NCBI Accession	NP_116090.2
KEGG	hsa:84787
String	9606.ENSP00000255613
Molecular Weight	Calculated MW: 52.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat KMT5C.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue