Spleen Associated Tyrosine Kinase Phospho-Tyr323 (SYK pY323) Antibody

Catalogue No: abx000342
Price: £230.00
(Size: 50 µl)

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Datasheet SDS
SYK (pY323) Antibody is a Rabbit Polyclonal antibody against SYK (pY323). This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target SYK (pY323)
Clonality Polyclonal
Target Modification Tyr323
Modification Phosphorylation
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y323 of human SYK.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P43405 (UniProt, ExPASy)
UniProt Entry Name KSYK_HUMAN
Gene Symbol SYK
GeneID 6850
KEGG hsa:6850
String 9606.ENSP00000364907
Molecular Weight Calculated MW: 69 kDa, 72 kDa
Observed MW: 72 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SYK (pY323)

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